Archives of Surgery
Inappropriate Antibiotic Use in Soft Tissue Infections
Hypothesis: Many soft tissue infections treated with surgical drainage resolve even when treated with antibiotics not active against the organism isolated from the infection.
Design: Retrospective.
Setting: Integrated Soft Tissue Infection Services clinic.
Patients: All patients treated from July 19, 2000, to August 1, 2001, who underwent surgical drainage of a soft tissue infection and had microbiological culture results.
Main Outcome Measures: Documented resolution of the infection with drainage of the abscess and antibiotic therapy alone was deemed a cure. An infection resulting in death or other surgical therapy was deemed a failure. Therapy was appropriate when the organism was sensitive to prescribed antibiotics and was inappropriate when the organism was insensitive.
Results: The study included 376 patients with 450 infections. Staphylococcus aureus as the primary organism was isolated from 441 of the cultures. Methicillin sodium–sensitive S aureus and methicillin-resistant S aureus were . . . [Full Text of this Article]
Archives of Facial Plast Surgery
Archives of Dermatology