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Ross EV, Miller C, Meehan K, McKinlay J, Sajben P, Trafeli JP, Barnette DJ
Dermatol Surg. 2001;27:709-715

Background: The CO₂ laser is normally described as an aggressive resurfacing tool, whereas the erbium:YAG laser has enjoyed a reputation as the ideal tool for superficial resurfacing. The implication from many studies is that the CO₂ laser is incapable of "minimally invasive" resurfacing.

Objective: To compare a short-pulsed CO₂ laser with an Er:YAG laser over a range of parameters intended to produce equivalent microscopic and clinical injuries.

Methods: A prospective, randomized, comparative interventional trial was conducted in a tertiary care teaching hospital. Thirteen patients with facial wrinkles were enrolled in the study. A side-by-side comparison was performed using periorbital and perioral regions as treatment sites. One side was treated with a pulsed CO₂ laser and the other with an Er:YAG laser. Postauricular skin was treated in an identical fashion to the study sites . . . [Full Text of this Article]

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