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Microbiologic Assessment of Multidose Restylane for Facial Augmentation
Michael G. Brandt, MD;
Maha Al Gilani, MD;
Janet Balderston, MD;
Ross Davidson, MD;
Corey C. Moore, MD;
Mark Taylor, MD
Arch Facial Plast Surg. 2009;11(4):271-273.
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Since 1996, Restylane (Q-Medical, Uppsala, Sweden; distributed by Medicis Aesthetics Canada, Toronto, Ontario), a nonanimal stabilized hyaluronic acid (NASHA), has been used as a soft-tissue filler in Europe and Canada and, more recently, the United States. The longstanding safety, efficacy, and low immunogenicity profile of Restylane and the other NASHA fillers have made them the preferred choice for facial soft-tissue augmentation.1-5 Restylane is provided in prefilled 0.5-mL and 1.0-mL single-dose syringes. Although the manufacturer does not recommend its use as a multidose syringe, based largely on the cost of the product, it has been our practice to save any unused portion of the prefilled syringe for future dosing in the same patient. This practice has been well received by patients because they occasionally require a repeated injection after 2 . . . [Full Text of this Article]Methods
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