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Arch Facial Plast Surg. 2008;10(1):68-69.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Archives of Dermatology

Five-Year Follow-up of a Randomized, Prospective Trial of Topical Methyl Aminolevulinate Photodynamic Therapy vs Surgery for Nodular Basal Cell Carcinoma

Objective: To compare 5-year lesion recurrence rates in primary nodular basal cell carcinoma treated with topical methyl aminolevulinate photodynamic therapy (PDT) or simple excision surgery.

Design: Prospective, randomized, multicenter study.

Setting: University hospital dermatology departments.

Patients: A total of 97 patients, 50 with 53 lesions treated with methyl aminolevulinate PDT and 47 with 52 lesions treated by excision surgery, were included in the per protocol analysis. Of the lesions treated with methyl aminolevulinate PDT and surgery, 49 and 52, respectively, showed complete clinical response at 3 months after treatment and were observed for long-term outcome evaluation.

Interventions: Topical methyl aminolevulinate cream, 160 mg/g, applied for 3 hours before illumination (75 J/cm² of red light at 570 to 670 nm) on 2 or 4 occasions (12 [23%] of 53 lesions); or . . . [Full Text of this Article]