 |
|
Recovery From Deep-Plane Rhytidectomy Following Unilateral Wound Treatment With Autologous Platelet Gel
A Pilot Study
David M. Powell, MD;
Edward Chang, MD;
Edward H. Farrior, MD
Arch Facial Plast Surg. 2001;3:245-250.
Objective To determine the effects of treatment with
autologous platelet-rich plasma mixed with thrombin and calcium
chloride to form an autologous platelet gel (APG) on postoperative
recovery from deep-plane rhytidectomy.
Study Design A prospective, randomized, controlled pilot
study.
Setting An accredited ambulatory facial plastic surgery
center.
Patients Healthy volunteer women (N = 8)
undergoing rhytidectomy.
Intervention Unilateral autologous platelet-rich plasma wound
treatment during standard deep-plane rhytidectomy.
Main Outcome Measures Staged postoperative facial photographs
were graded in a blinded fashion by 3 facial plastic
surgeon reviewers for postoperative ecchymosis and edema. Each facial
side treated with APG that demonstrated less edema or ecchymosis than
the non–APG-treated side was designated a positive response;
otherwise, the response was equal (no difference) or
negative (untreated side had less edema or
ecchymosis).
Results Twenty-one positive and 21 equal responses were
observed compared with 8 negative ones. Of 20 unanimous observations,
15 were positive, only 3 equal, and 1 negative.
Conclusions Treatment with APG may prevent or improve edema or
ecchymosis after deep-plane rhytidectomy. This trend is more apparent
for ecchymosis than for edema, and is chiefly demonstrable in the early
phases of recovery. These observations are consistent with previous
reports of cell tissue culture and wound response to concentrated
platelet product.
From
the Division of Facial Plastic and Reconstructive Surgery, Department
of Otolaryngology, The Ohio State University, Columbus (Dr
Powell), and the Farrior Facial Plastic and Reconstructive Surgery
Center, Tampa, Fla (Drs Farrior and Chang). The authors have
no financial relationship to Blood Recovery Systems Inc and received no
financial compensation for using its services in the performance of
this investigation.
RELATED ARTICLE
Promising Results From a Preliminary Study of Autologous Platelet Gel in Face-lift Surgery
Kriston J. Kent
Arch Facial Plast Surg. 2001;3(4):251.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
New Developments in Wound Healing Relevant to Facial Plastic Surgery
Hom
Arch Facial Plast Surg 2008;10:402-406.
ABSTRACT
| FULL TEXT
The Healing Effects of Autologous Platelet Gel on Acute Human Skin Wounds
Hom et al.
Arch Facial Plast Surg 2007;9:174-183.
ABSTRACT
| FULL TEXT
Modulation of Wound Response and Soft Tissue Ingrowth in Synthetic and Allogeneic Implants With Platelet Concentrate
Sclafani et al.
Arch Facial Plast Surg 2005;7:163-169.
ABSTRACT
| FULL TEXT
Promising Results From a Preliminary Study of Autologous Platelet Gel in Face-lift Surgery
Kent
Arch Facial Plast Surg 2001;3:251-251.
FULL TEXT
|
